The human gut harbors diverse microbes that play a fundamental role in the well-being of their host. The constituents of the microbiota—bacteria, viruses, and eukaryotes—have been shown to interact with one another and with the host immune system in ways that influence the development of disease.
Here are a few links between gut bacteria and health :
- Mood Disorders – Bacteria in the gut activate neural pathways and central nervous system singling systems. Gut dysbiosis, especially a lack of beneficial bacterial strains, is linked to depression and anxiety, with more than a third of depression sufferers also having a leaky gut.
- Obsessive Compulsive Disorder – Dysfunction of the gut microbiome, perhaps related to high stress and/or antibiotic use, is linked to OCD.
- Schizophrenia – Mice studies link a lack of normal bacteria with changes in brain development and schizophrenic behaviour. Human infants born prematurely are known to lack biodiversity in their guts and be at a higher risk of schizophrenia.
- Autism – Autism often co-occurs with gastrointestinal issues like leaky gut and irritable bowel syndrome.
- Multiple Sclerosis – Dysbiosis and the resulting loss of balance in gastrointestinal immune responses are lined to the development of MS and may explain why MS symptoms can be mitigated with therapeutic diets.
- Cardiovascular Disease – Certain grain loving bacteria are known to also convert L-carnitine, a protein rich in red meat, into an atherogenic compound called TMAO, raining the risk of cardiovascular disease.
- Asthma and Allergies – Low diversity of gut bacteria, especially early in life, is linked to increased risk of asthma and allergies.
- Obesity – Gut microbes can impact metabolism via singling pathways in the gut, with effects on inflammation, insulin resistance, and deposition of energy in fat stores. A number of studies show specific microbial patterns associated with obesity.
- Diabetes – Diabetics have lower levels of beneficial strains of bacteria and skewed ratios of different strains, with lower numbers of gut microbes overall. Some compositional changes in gut microbiota appear to scale with glucose levels that is the higher a person’s glucose levels, the fewer total microbes and the more undesirable species of bacteria are likely to be found in that person’s gut.
- Inflammatory Bowel Disease – Abnormally high levels of certain undesirable strains of bacteria along with dysregulated immune responses to gut microbes may trigger the development and continuing symptoms of both Crohn’s diseases and ulcerative colitis.
- Irritable Bowel Syndrome – There is a definitive link between IBS and an overgrowth of bacteria in the small intestine (SIBO).
- Rheumatoid Arthritis – Studies have found link between low levels of probiotic bacteria and high levels of undesirable bacteria strains with autoimmune joint diseases like RA.
- Colorectal Cancer – Lower levels of beneficial bacteria as well as higher levels of certain sugar loving microbes in the gut are linked to increases risk and growth rates of colorectal cancer.
- Other Cancer – Dysbiosis is linked to increased risk of gastric, oesophageal, pancreatic, laryngeal, breast, and gallbladder carcinoma.