Are you trying to repair a leaky gut? Do you suffer from chronic digestive issues such as gas, bloating, indigestion, or constipation? Do you experience reflux after a meal? Or do you see pieces of undigested food or a fatty substance in your stool?  If so, your body may not be producing enough digestive enzymes, or your enzymes may not be working as well as they should. This is a common issue in patients with chronic disease.

Here are a few conditions in which you should take digestive enzymes :

• Digestive Diseases – If you have any type of digestive disease such as acid reflux, gas, bloating, leaky gut, irritable bowel syndrome (IBS), Crohn’s disease, ulcerative colitis, diverticulitis, malabsorption, diarrhoea or constipation, then digestive enzymes can help. Digestive enzymes can take stress off the stomach, pancreas, liver, gallbladder and small intestine by helping break down difficult to digest proteins, starches and fats.
• Age Related Enzyme Insufficiency – As we age, the acidity of our stomach acid becomes more alkaline. In respect of enzyme production, this means there’s an increasing likelihood the acidic “trigger” produced when chyme enters the intestine mat fail. If the acidity trigger fails, then the “signal” isn’t given to secretin, which in turn prevents pancreatic secretions from releasing.
• Hypochlorhydria – It’s not only the elderly who suffer from hypochlorhydria, or lack of stomach acid. Aside from a decrease in stomach acid failing to trigger reactions, the acid itself cannot break down foods to release minerals, vitamins and nutrients. Many micronutrients are “cleaved” or released from food while it’s in the stomach, if this action fails then there’s an automatic nutritional or enzymatic insufficiency.
• Liver Disease – Anyone with liver disease should be suspected as having a concurrent enzyme insufficiency. One of the more common conditions is known as alpha-1-antitrypsin deficiency, a genetic disorder that affects roughly one in 1500 people worldwide. Typically first affecting adults between 20-50 with breathing and other respiratory complaints, roughly 15 percent of adults develop liver disease.

Reference : https://draxe.com/nutrition/digestive-enzymes/